After the first medieval city enlargement of Berlin the St. Marienkirche / Church of Our Lady was built as a parish church for the new city parts. Like the rebuilt Nikolai church, the ruins of the Franciscan minister and the chapel of the Heiliggeist hospital, St. Marienkirche is an important architectural testimony of Berlin's early history. In contrast to the others St. Marien is the only building that is still used for church services today.
The gothic church has been fundamentally rebuilt in baroque, when the church should turn into a hall for sermons by the installation of the pulpit by Andreas Schlüter. The symbolism of the gothic hall had to move for considerations of a more rational, functional kind. In 1893/94 a voluminous renovation was initiated by H. Blankenstein. His efforts led to St. Marien as it looks today (facade of the extensions on the South side, organ gallery, ground floor etc.).

The Protestant community of St. Marien preserves a long cultural heritage. Since the Middle Ages the provost of Berlin has been priest of St. Nikolai and St. Marien at the same time. After the secularisation of St. Nikolai St. Marien also turned into the provost's see. It is this tradition of St. Marien that mades it see of the Protestant church in Berlin-Brandenburg. From the end of World War II until today St. Marien's priest is bishop of Berlin-Brandenburg. And St. Marienkirche is a place for preachers from all over the world (Martin Luther King preached here). It 's a place for church services and events of national church's belonging and it's an important meeting point of church and community in the heart of Berlin.